Indole3™, 200 mg, 60 Vegetable Capsules
Indole-3-Carbinol I3C supplement
- Powerful antioxidant*
- Cellular support for healthy cells*
- Dietary Supplement
Indole-3-Carbinol Side Effects and Safety
No major indole-3-carbinol supplement side effects have yet been reported in the medical literature but this nutraceutical has not yet been studied extensively in humans.
Where is it found?
Indole-3-Carbinol is a naturally occurring phytochemical (a substance produced by a plant) found in cruciferous vegetables. It is a powerful antioxidant helping to prevent cellular damage.*
As a dietary supplement, healthy adults take one capsule in the morning with or without food, or as recommended by a qualified healthcare professional.
|Serving Size: 1 Capsule|
|Servings Per Bottle: 60 Capsules|
|Amount Per Capsule||% Daily Value|
|†Daily Value or Recommended Daily Intake Not Established
Other Ingredients: Modified Cellulose (Hypromellose Vegetable Capsule) and Magnesium Stearate.
Due to sourcing or manufacturing updates, the ingredients or packaging of our products may differ from the information provided on the website. Always refer to the product packaging received for accurate details before use.
Combining with prescription medication, chemotherapy drugs
Q. I am a cancer specialist, oncologist, working with breast cancer in several forms of cancer in my patients. Recently I have had 2 patients ask me about Indole 3 Carbinol and whether they can take it with chemotherapy drugs. What should I tell them?
A. We are not in a position to offer specific advice, but you may search Medline for studies similar to this:
Clin Cancer Res. 2016. Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances. Chronic lymphocytic leukemia (CLL) still is lacking a cure. Indole-3-carbinol (I3C) is a natural product clinically tested. The effect of I3C, Fludarabine, and combinations of both drugs on CLL cells from patients representing different IGHV mutation status, cytogenetic alterations, p53 functionality, and treatment resistances was tested, as well as the toxicity of these treatments in mice. I3C in combination with fludarabine is highly cytotoxic in CLL cells from refractory patients and those with p53 deficiency. The striking dose reduction index for fludarabine in combination with I3C would reduce fludarabine toxicity while having a similar or better anti-CLL effectiveness.
Q. Hello, I would like to know if you have any outlets here in Australia; I live in Sydney and would be interested to purchase some of your products - How much would for instance the I3c product with postage / shipping?
A. These nutritional products can be shipped to Australia by global express.