Indole-3-Carbinol, 200 mg, 60 Veg Caps | Advance Physician Formulas

Indole-3-Carbinol I3C supplement
Top quality

Powerful antioxidant*
Cellular support for healthy cells*
Dietary Supplement

Indole-3-Carbinol Side Effects and Safety
No major indole-3-carbinol supplement side effects have yet been reported in the medical literature but this nutraceutical has not yet been studied extensively in humans.

Where is it found?
Indole-3-Carbinol is a naturally occurring phytochemical (a substance produced by a plant) found in cruciferous vegetables. It is a powerful antioxidant helping to prevent cellular damage.*

Suggested Use:
As a dietary supplement, healthy adults take one capsule in the morning with or without food, or as recommended by a qualified healthcare professional.

Supplement Facts
Serving Size: 1 Capsule
Servings Per Bottle: 60 Capsules
	Amount Per Capsule	% Daily Value
Indole-3-Carbinol	200 mg	†
†Daily Value or Recommended Daily Intake Not Established Other Ingredients: Vegetable Capsule (Modified Cellulose), Rice Flour.

Combining with prescription medication, chemotherapy drugs
Q. I am a cancer specialist, oncologist, working with breast cancer in several forms of cancer in my patients. Recently I have had 2 patients ask me about Indole 3 Carbinol and whether they can take it with chemotherapy drugs. What should I tell them?
A. We are not in a position to offer specific advice, but you may search Medline for studies similar to this:
Clin Cancer Res. 2016. Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances. Chronic lymphocytic leukemia (CLL) still is lacking a cure. Indole-3-carbinol (I3C) is a natural product clinically tested. The effect of I3C, Fludarabine, and combinations of both drugs on CLL cells from patients representing different IGHV mutation status, cytogenetic alterations, p53 functionality, and treatment resistances was tested, as well as the toxicity of these treatments in mice. I3C in combination with fludarabine is highly cytotoxic in CLL cells from refractory patients and those with p53 deficiency. The striking dose reduction index for fludarabine in combination with I3C would reduce fludarabine toxicity while having a similar or better anti-CLL effectiveness.

Shipping overseas
Q. Hello, I would like to know if you have any outlets here in Australia; I live in Sydney and would be interested to purchase some of your products - How much would for instance the I3c product with postage / shipping?
A. These nutritional products can be shipped to Australia by global express for 30 dollars.

Combining with prescription medication, chemotherapy drugs
Q. I am a cancer specialist, oncologist, working with breast cancer in several forms of cancer in my patients. Recently I have had 2 patients ask me about Indole 3 Carbinol and whether they can take it with chemotherapy drugs. What should I tell them?
A. We are not in a position to offer specific advice, but you may search Medline for studies similar to this:
Clin Cancer Res. 2016. Indole-3-Carbinol Synergizes with and Restores Fludarabine Sensitivity in Chronic Lymphocytic Leukemia Cells Irrespective of p53 Activity and Treatment Resistances. Chronic lymphocytic leukemia (CLL) still is lacking a cure. Indole-3-carbinol (I3C) is a natural product clinically tested. The effect of I3C, Fludarabine, and combinations of both drugs on CLL cells from patients representing different IGHV mutation status, cytogenetic alterations, p53 functionality, and treatment resistances was tested, as well as the toxicity of these treatments in mice. I3C in combination with fludarabine is highly cytotoxic in CLL cells from refractory patients and those with p53 deficiency. The striking dose reduction index for fludarabine in combination with I3C would reduce fludarabine toxicity while having a similar or better anti-CLL effectiveness.

Shipping overseas
Q. Hello, I would like to know if you have any outlets here in Australia; I live in Sydney and would be interested to purchase some of your products - How much would for instance the I3c product with postage / shipping?
A. These nutritional products can be shipped to Australia by global express for 30 dollars.