Compounds in this root inhibit cyclooxygenase (COX), an enzyme responsible for formation of substances called prostanoids, including prostaglandins, prostacyclin and thromboxane, some of which cause inflammation. There are various types of COX enzymes, named type 1, 2, and 3. Ginger has been found to inhibit type COX-2 which makes it beneficial in the treatment of various forms of arthritis. See http://www.raysahelian.com/cyclooxygenase.html.