Active hexose correlated compound (AHCC) is an extract of a basidiomycete mushroom that is used as a supplement by some cancer patients undergoing chemotherapy; it is thought to enhance the therapeutic effects and reduce the side effects of some chemotherapy drugs. In the first study, AHCC given to rats was able to reduce arabinoside-induced hair loss, and 6-mercaptopurine- and methotrexate-induced liver injury. In the second study, use of AHCC reduced damage to the immune system, kidneys, and the liver when it was combined with chemotherapy drugs such as cisplatin. See

     Comments: If additional studies in humans confirm these findings, AHCC may become a useful supplement in some cancer patients undergoing chemotherapy with certain drugs.