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In an article titled, "L-carnosine as an adjuvant to fluvoxamine in treatment of obsessive compulsive disorder: A randomized double-blind study," investigators tried to find out if any natural supplements added to an antidepressant medication could be of additional benefit in reducing the symptoms of OCD. Forty-four patients diagnosed with moderate to severe OCD were treated with fluvoxamine either alone or with the addition of L-carnosine for a period of 10 weeks. The brand name of fluvoxamine is Luvox. It is considered a SSRI medication similar to Prozac, Paxil, and Zoloft and mostly acts on the serotonin system in the brain.

The results were good. The addition of L-carnosine led to a significant reduction of obsessive-compulsive symptoms. I always find it interesting and encouraging how supplements can be used either as a replacement or in addition to medications to help doctors find solutions to the many physical and mental conditions that people suffer from. As to the dosage recommendations, I tend to think that for treatment purposes the dosage should be limited to 500 mg or less a day, especially when combined with Luvox or other anti-depressants. It may even be a good idea to reduce the dosage of the SSRI when adding carnosine supplementation. Some researchers also claim that carnosine has anti-aging potential but this has yet to be tested in humans. To those who wish to take carnosine for its potential anti-aging benefits, I suggest opening a 500 mg capsule and only using a small portion each morning. The whole 500 mg capsule could last a week.

Disclaimer: People should be taking the least amount of prescription drugs that provide adequate treatment, and to regularly monitor and review what is being taken and how much. This applies to most supplements, too. Please do not make any changes in your treatment without first discussing it with your health care provider. Statements made, or products sold through this website, have not been evaluated by the United States Food and Drug Administration. They are not intended to diagnose, treat, cure or prevent any disease.

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